• Svetlana Dokudovskaya, DR2 CNRS
• Yegor Vassetzky, DR1 CNRS
• Joëlle Wiels, DREM CNRS
• Marc Lipinski, DREM CNRS
• Yahir Alberto Loissel Baltazar, PhD student (Université Paris-Saclay)
• Anna Shmakova, PhD student (Université Paris-Saclay)
• Zhenrui Pan, PhD student (Université Paris-Saclay-CSC)
• Anna Karpukhina, PhD student (Université Paris-Saclay)
• Junyi Feng,  PhD student (Université Paris-Saclay-CSC)
• Haoran Chai, PhD student (Université Paris-Saclay-CSC)

Major publications

• Shmakova, A, Lomov, N., Viushkov, V., Tsfasman, T.,  Kozhevnikova, Y., Sokolova, D., Pokrovsky, V., Syrkina, M., Germini, D., Rubtsov, M.,  and VASSETZKY, Y.S. (2022) Cell models with inducible oncogenic translocations allow to evaluate the potential of drugs to favor secondary translocations. Cancer Communications, DOI: 10.1002/cac2.12370

Chromatindynamics and metabolism in cancer

This group belongs to the UMR 9018 - Metabolic and systemic aspects of oncogenesis for novel therapeutic approaches (Metsy)

We are working on the founding events in oncogenesis. Our approach allows us to search for early biomarkers of cancers and develop cancer-preventive approaches.

Lab members

Team leader: Anne Dupressoir

Researchers :

• Anne DUPRESSOIR, CRHC Inserm
• Odile HEIDMANN, CRCN CNRS
• Thierry HEIDMANN, DREM
• Gérard PIERRON, DREM
• Marianne MANGENEY, CRHC CNRS
• Agathe BACQUIN, Researcher
• Grégoire MARTIN, Researcher
• Guillaume MOUSSEAU, Researcher
• Baptiste ROELENS, Researcher
• Jhen TSANG, Researcher
• Maude MARCHAIS, Researcher

ITA :

Publications

Endogenous retroviral envelopes / syncytin genes

Mousseau G, Préault N, Souquère S, Bireau C, Cassonet P, Bacquin A, Beck L, Pierron G, Jacob Y, Dupressoir A, and Heidmann T. The sodium dependent phosphate transporter PiT1/Slc20a1 is the receptor for the endogenous retroviral envelope syncytin-B involved in mouse placenta formation. J Virol 2024 Sep 17 e0091524  Editor's Pick
 

Physiology and Molecular Pathology of Endogenous and Infectious Retroviruses

This team belongs to the UMR 9196 : Physiology and Molecular Pathology of Endogenous and Infectious Retroviruses

The Unit's work, historically focused on retroelements and retroviruses, has made significant contributions to:

Lab members

Researchers / Teacher-researchers / PH:

• Jacques GRILL (MD, PhD, HDR)
• Marie-Anne DEBILY (MCU, Univ. d’Evry Val d’Essonne, HDR)
• David CASTEL (CRCN, INSERM, HDR)
• Gilles VASSAL (PU-PH, Univ. Paris-Saclay, HDR)
• Marco BRUSCHI (Postdoctorant, GR)
• Christelle DUFOUR (PH, GR)
• Léa GUERRINI (PH, GR)

Engineers / Technicians: 

Major publications

• 1: Werbrouck C, Evangelista CCS, Lobón-Iglesias MJ, Barret E, Le Teuff G, Merlevede J, Brusini R, Kergrohen T, Mondini M, Bolle S, Varlet P, Beccaria K, Boddaert N, Puget S, Grill J, Debily MA, Castel D. TP53 Pathway Alterations Drive Radioresistance in Diffuse Intrinsic Pontine Gliomas (DIPG). Clin Cancer Res. 2019 Nov 15; 25(22):6788-6800. doi: 10.1158/1078-0432.CCR-19-0126.

Genomics and oncogenesis of childhood brain tumors

This team belongs to the UMR 981 - Molecular predictors and new targets in oncology

The GOBT team is dedicated to understand the development mechanisms of pediatric brain tumors (in particular gliomas). We are looking for biological markers to identify these tumors more precisely, to understand their origin, to define their prognosis and to invent new treatments.

Lab members

• Gerard Mazón (CR, team co-leader)
• Eric Le Cam (DR, team co-leader)
• Pauline Dupaigne (CR)
• Sonia Baconnais (IR)
• Clara Basto (PhD Student, UPS)
• Amina Serrar (M2 student)
• Barbara Ly (M2 Student)
• Raquel Iriarte (M1 Student)

We are open for prospective inquires for M2/PhD/Tech positions. Please contact us if you are seeking to apply for competitive calls for post-doctoral positions with a hosting laboratory.

Recent Past members (their current position):