The hematopoietic niche group

Hematopoietic tissue aging

This group belongs to the UMR 1287 - Hematopoietic stem cells and the development of myeloid malignancies

• Guillaume Montagnac, PI Inserm
• Nadia Elkhatib, Inserm staff scientist (CRCN)
• Francesco Baschieri, post-doc
• Kseniia Porshneva, post-doc
• Enzo Bresteau, post-doc
• Nathalie Ly, Engineer
• Julie Bruna-Gauchoux, PhD student
• Samuel Tettarasar, PhD student

Major publications

• Lock JG, Baschieri F, Jones MC, Humphries JD, Montagnac G, Strömblad S, Humphries MJ. Clathrin-containing adhesion complexes. J Cell Biol. 2019 Jul 1;218(7):2086-2095. doi: 10.1083/jcb.201811160. Epub 2019 Jun 17.
• Baschieri F, Dayot S, Elkhatib N, Ly N, Capmany A, Schauer K, Betz T, Vignjevic DM, Poincloux R, Montagnac G. Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures. Nat Commun. 2018 Sep 20;9(1):3825. doi: 10.1038/s41467-018-06367-y.

Endocytosis, cytoskeleton and cell migration

This team belongs to the UMR 1279 - Tumor cell dynamics

The overall objective of our lab is to understand how the mechanical properties of the tumoral environment influence cancer cell migration.

Team

Team leader

• Thomas MERCHER, DR2, INSERM
• Marie-Laure ARCANGELI, CRCN, INSERM

Members

• Muriel GAUDRY, CRCE, INSERM
• Hélène CAVE, PU-PH, Université Paris-Cité
• Marion STRULLU, MCU-PH, Université Paris-Cité
• Chloé ARFEUILLE, PH, Université Paris-Cité
• Charlotte RIGAUD, PH, Gustave Roussy
• Julie RIVIÈRE, IR, INSERM
• Zakia AID, Engineer
• Elie ROBERT, Bioinformatic engineer
• Kimberly TO, Engineer
• Mélanie VAR, Project Manager

Recent publications

• Fagnan A, Aid Z, Baille M, Drakul A, Robert E, Lopez CK, Thirant C, Lecluse Y, Rivière J, Ignacimouttou C, Salmoiraghi S, Anguita E, Naimo A, Marzac C, Pflumio F, Malinge S, Wichmann C, Huang Y, Lobry C, Chaumeil J, Soler E, Bourquin JP, Nerlov C, Bernard OA, Schwaller J, Mercher T. The ETO2 transcriptional co-factor maintains acute leukemia by driving a MYB/EP300-dependent stemness program.
  Hemasphere. 2024. in press

The team Biology of pediatric leukemia is part of the UMR 1170 Molecular dynamics of hematopoietic transformation.

Group : From haematopoietic stem cell to megakaryocyte

This group belongs to the UMR 1170 “Normal and pathological haematopoiesis”

Group TLS Polymerases: Genome Plasticity and Cancers

This group belongs to the team "TLS Polymerases: Genome Plasticity and Cancers"