Myeloid cell development and function : lab members

Myeloid cell development and function: lab members

  • Florent Ginhoux: Team Leader
  • Safia Zouggar: Administrative Manager of the Team
  • Aymeric Silvin: Researcher
  • Claudia Pasqualini: Physician-Researcher
  • Alessia Bagattin-Gallazzini: Researcher
  • Grégoire Gessain: Physician Pathologist-Researcher

Advanced T cell therapy - Lab members

Advanced T cell therapy: lab members

  • Laurie Menger PhD, HDR CRCN INSERM
  • Aurélien Sutra Del Galy MD PhD, Data scientist
  • Marguerite Laprie Sentenac, PharmD, PhD student
  • Albane Simon, PhD student
  • Chloe Slater, PhD student, collab Massachusetts General Hospital USA
  • Chuang Dong, Data scientist
  • Laetitia Perrin, Engineer
  • Janany Kandiah, Engineer

 

 

Thérapies cellulaires avancées - publications

Advanced T cell therapy - Major publications

  • Ablation of FAS confers allogeneic CD3- CAR T cells with resistance to rejection by T cells and natural killer cells. Menegatti S, Lopez-Cobo S, Sutra Del Galy A, Fuentealba J, Silva L, Perrin L, Heurtebise-Chrétien S, Pottez-Jouatte V, Darbois A, Burgdorf N, Privat AL, Simon A, Laprie-Sentenac M, Saitakis M, Wick B, Webber BR, Moriarity BS, Lantz O, Amigorena S, Menger L. Nat Biomed Eng. 2024 Nov 18. doi: 10.1038/s41551-024-01282-8.

Advanced T cell therapy

Advanced T cell therapy : current research

This research team belongs to the UMR 1015 - Tumor immunology and immunotherapies

We develop genome editing approaches derived from CRISPR-cas9 technology (inactivation, activation, base editing, genome-wide) to understand the biology of T cells but also improve the composition, functionality, and persistence of therapeutic cell products, CAR-T, and TILs (tumor-infiltrating lymphocytes).

Research Call for Applications 2025

Research - Call for Applications 2025

Gustave Roussy Prize

Gustave Roussy portrait

 

The Institute is launching the Gustave Roussy Prize to mark the 150th anniversary of the birth of its visionary founder.
 

 

 

(Epi)genome replication - publications

(Epi)genome replication - Publications

  • Fajri N, Petryk N#. Monitoring and quantifying replication fork dynamics with high-throughput methods. Commun Biol. 2024 Jun 14;7(1):729. doi: 10.1038/s42003-024-06412-1.
  • Wu X*, Liu Y*, Daubenton-Carafa Y ; Thermes C ; Chen CL#, Hyrien O#, Petryk N#. Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing. Nature protocols. 2023 Apr;18(4):1260-1295. doi: 10.1038/s41596-022-00793-5.

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